In 1971, John O´Keefe discovered the first component of this positioning system. He found that a type of nerve cell in an area of the brain called the hippocampus that was always activated when a rat was at a certain place in a room. Other nerve cells were activated when the rat was at other places. O´Keefe concluded that these “place cells” formed a map of the room.
Nei primi anni 2000 May-Britt Moser e Edvard I. Moser scoprirono un'altra area coinvolta, la corteccia entorinale, dove le cellule griglia costituiscono un valido sistema di posizionamento
More than three decades later, in 2005, May-Britt and Edvard Moser discovered another key component of the brain’s positioning system. They identified another type of nerve cell, which they called “grid cells”, that generate a coordinate system and allow for precise positioning and pathfinding. Their subsequent research showed how place and grid cells make it possible to determine position and to navigate.Qui, sul sito del Nobel Prize, una rassegna biografica dei vincitori più una breve descrizione del loro lavoro e delle pubblicazioni.